A daily adaptogen formulation designed to support stress modulation, mood stability, and sleep quality during menopause and perimenopause. Combines clinically studied Ashwagandha with black pepper to optimize bioavailability.
All batch testing and Certificates of Analysis are available in the Menopause Science Trust Center.
Clinical Profile
Targets
-
Stress response and cortisol regulation
-
Mood variability
-
Sleep latency and continuity
-
Nervous system support during hormonal transition
Primary Active
Organic Ashwagandha Root (Withania somnifera) — 1000 mg per serving
An adaptogenic herb shown to support stress resilience, mood stability, and sleep regulation.
Formulation Rationale
Hormonal changes and stress can disrupt mood regulation and sleep patterns. This formulation combines Ashwagandha with black pepper to enhance absorption and maximize physiological impact.
Organic Black Pepper (Piper nigrum) — Increases bioavailability of active constituents in Ashwagandha.
The formulation is designed for daily use to support multiple pathways involved in stress response, mood regulation, and sleep quality without sedation
Key Characteristics
-
Clinically aligned Ashwagandha dosage
-
Black pepper–enhanced absorption
-
Vegan, non-GMO, gluten-free, sugar-free
-
Free from artificial fillers and preservatives
-
Manufactured in a GMP-certified, FDA-registered facility
Full Ingredient List
Organic Ashwagandha Root
Organic Black Pepper
Vegetable Capsule
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Trust Center Verified
Comprehensive analysis of clinical research and evidence*
Mood & Sleep Support By Menopause Science
Clinical research shows that up to 80% of perimenopausal women experience mood disturbances and sleep problems. Mood and Sleep Support provides organic ashwagandha root enhanced with black pepper extract for maximum bioavailability and effectiveness.*
View Product
Research Summary
Clinical research suggests that ashwagandha supplementation may significantly reduce perceived stress, anxiety, and improve sleep quality while supporting healthy cortisol levels. Studies specifically in perimenopausal women suggest that ashwagandha may reduce total menopause symptom scores, with particular benefits for psychological symptoms, mood disturbances, and sleep disruption. The addition of black pepper extract (piperine) may enhance absorption, potentially ensuring optimal therapeutic benefits.*
Research at a Glance
|
Ingredient |
Population Studied |
Studied Benefit(s) |
Research Link |
|
Ashwagandha (600mg daily) |
100 perimenopausal women aged 45-60 |
8-week RCT: Significant reduction in total menopause symptoms, anxiety, irritability, and depressive symptoms vs placebo |
|
|
Ashwagandha (300mg 2x daily) |
64 adults with chronic stress |
60-day RCT: 44% reduction in stress scores, significant reduction in anxiety and cortisol levels |
|
|
Ashwagandha (240mg daily) |
60 stressed adults |
60-day RCT: Significant reduction in anxiety (HAM-A scale) and morning cortisol levels vs placebo |
|
|
Ashwagandha |
400 participants across 5 studies |
Meta-analysis: Significant improvement in overall sleep quality, sleep onset latency, and total sleep time |
|
|
Ashwagandha (300mg 2x daily) |
60 insomnia patients |
10-week RCT: Significant improvement in sleep onset latency, sleep efficiency, and quality vs placebo |
|
|
Black Pepper (Piperine) |
Various supplement studies |
Bioavailability enhancer: Increases absorption of herbal compounds by inhibiting liver enzymes |
Plain Language Summary
Ashwagandha has been studied in adults, including women going through perimenopause, for its potential role in reducing stress, supporting mood, and improving sleep. Several clinical trials suggest it may help lower perceived anxiety, support healthier cortisol levels, and improve sleep quality. When combined with black pepper extract, absorption may be enhanced, which could increase effectiveness.*
Key Citations
Primary Research in Perimenopausal Women:
-
Gopal S, et al. Effect of an ashwagandha (Withania Somnifera) root extract on climacteric symptoms in women during perimenopause: A randomized, double-blind, placebo-controlled study. J Obstet Gynaecol Res. 2021;47(12):4414-4425. PubMed: 34553463
Supporting Stress and Anxiety Research:
-
Chandrasekhar K, et al. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012;34(3):255-262. PubMed: 23439798
-
Lopresti AL, et al. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract. Medicine. 2019;98(37):e17186. Medicine Journal
Sleep Research:
-
Cheah KL, et al. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis. PLoS One. 2021;16(9):e0257843. PubMed: 34559859
-
Langade D, et al. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus. 2019;11(9):e5797. PMC: 6827862
Bioavailability Enhancement Research:
-
Dudhatra GB, et al. A comprehensive review on pharmacotherapeutics of herbal bioenhancers. ScientificWorldJournal. 2012;2012:637953. PMC: 3634921
Tired of Crying at Commercials and Staring at the Ceiling?
Stop sobbing over paper towel ads. Add to cart instead and try Mood & Sleep Support by Menopause Science today.
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Important Disclaimer
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult with your healthcare provider before starting any new supplement regimen, especially if you have pre-existing health conditions or are taking medications.
The research cited represents studies conducted on individual ingredients and may not reflect the specific formulation of this product. Individual results may vary based on sleep hygiene, stress levels, health status, and other factors. The research cited represents potential benefits and does not guarantee specific outcomes for all users.
Menopause Science
Ashwagandha + Black Pepper Complex
Ashwagandha + Black Pepper Complex
Every purchase funds 5% toward menopause research that medicine has ignored for decades
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Description
Description
A daily adaptogen formulation designed to support stress modulation, mood stability, and sleep quality during menopause and perimenopause. Combines clinically studied Ashwagandha with black pepper to optimize bioavailability.
All batch testing and Certificates of Analysis are available in the Menopause Science Trust Center.
Clinical Profile
Targets
-
Stress response and cortisol regulation
-
Mood variability
-
Sleep latency and continuity
-
Nervous system support during hormonal transition
Primary Active
Organic Ashwagandha Root (Withania somnifera) — 1000 mg per serving
An adaptogenic herb shown to support stress resilience, mood stability, and sleep regulation.
Formulation Rationale
Hormonal changes and stress can disrupt mood regulation and sleep patterns. This formulation combines Ashwagandha with black pepper to enhance absorption and maximize physiological impact.
Organic Black Pepper (Piper nigrum) — Increases bioavailability of active constituents in Ashwagandha.
The formulation is designed for daily use to support multiple pathways involved in stress response, mood regulation, and sleep quality without sedation
Key Characteristics
-
Clinically aligned Ashwagandha dosage
-
Black pepper–enhanced absorption
-
Vegan, non-GMO, gluten-free, sugar-free
-
Free from artificial fillers and preservatives
-
Manufactured in a GMP-certified, FDA-registered facility
Full Ingredient List
Organic Ashwagandha Root
Organic Black Pepper
Vegetable Capsule
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Trust Center Verified
Comprehensive analysis of clinical research and evidence*
Mood & Sleep Support By Menopause Science
Clinical research shows that up to 80% of perimenopausal women experience mood disturbances and sleep problems. Mood and Sleep Support provides organic ashwagandha root enhanced with black pepper extract for maximum bioavailability and effectiveness.*
View Product
Research Summary
Clinical research suggests that ashwagandha supplementation may significantly reduce perceived stress, anxiety, and improve sleep quality while supporting healthy cortisol levels. Studies specifically in perimenopausal women suggest that ashwagandha may reduce total menopause symptom scores, with particular benefits for psychological symptoms, mood disturbances, and sleep disruption. The addition of black pepper extract (piperine) may enhance absorption, potentially ensuring optimal therapeutic benefits.*
Research at a Glance
|
Ingredient |
Population Studied |
Studied Benefit(s) |
Research Link |
|
Ashwagandha (600mg daily) |
100 perimenopausal women aged 45-60 |
8-week RCT: Significant reduction in total menopause symptoms, anxiety, irritability, and depressive symptoms vs placebo |
|
|
Ashwagandha (300mg 2x daily) |
64 adults with chronic stress |
60-day RCT: 44% reduction in stress scores, significant reduction in anxiety and cortisol levels |
|
|
Ashwagandha (240mg daily) |
60 stressed adults |
60-day RCT: Significant reduction in anxiety (HAM-A scale) and morning cortisol levels vs placebo |
|
|
Ashwagandha |
400 participants across 5 studies |
Meta-analysis: Significant improvement in overall sleep quality, sleep onset latency, and total sleep time |
|
|
Ashwagandha (300mg 2x daily) |
60 insomnia patients |
10-week RCT: Significant improvement in sleep onset latency, sleep efficiency, and quality vs placebo |
|
|
Black Pepper (Piperine) |
Various supplement studies |
Bioavailability enhancer: Increases absorption of herbal compounds by inhibiting liver enzymes |
Plain Language Summary
Ashwagandha has been studied in adults, including women going through perimenopause, for its potential role in reducing stress, supporting mood, and improving sleep. Several clinical trials suggest it may help lower perceived anxiety, support healthier cortisol levels, and improve sleep quality. When combined with black pepper extract, absorption may be enhanced, which could increase effectiveness.*
Key Citations
Primary Research in Perimenopausal Women:
-
Gopal S, et al. Effect of an ashwagandha (Withania Somnifera) root extract on climacteric symptoms in women during perimenopause: A randomized, double-blind, placebo-controlled study. J Obstet Gynaecol Res. 2021;47(12):4414-4425. PubMed: 34553463
Supporting Stress and Anxiety Research:
-
Chandrasekhar K, et al. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012;34(3):255-262. PubMed: 23439798
-
Lopresti AL, et al. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract. Medicine. 2019;98(37):e17186. Medicine Journal
Sleep Research:
-
Cheah KL, et al. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis. PLoS One. 2021;16(9):e0257843. PubMed: 34559859
-
Langade D, et al. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus. 2019;11(9):e5797. PMC: 6827862
Bioavailability Enhancement Research:
-
Dudhatra GB, et al. A comprehensive review on pharmacotherapeutics of herbal bioenhancers. ScientificWorldJournal. 2012;2012:637953. PMC: 3634921
Tired of Crying at Commercials and Staring at the Ceiling?
Stop sobbing over paper towel ads. Add to cart instead and try Mood & Sleep Support by Menopause Science today.
Shop Now
Important Disclaimer
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult with your healthcare provider before starting any new supplement regimen, especially if you have pre-existing health conditions or are taking medications.
The research cited represents studies conducted on individual ingredients and may not reflect the specific formulation of this product. Individual results may vary based on sleep hygiene, stress levels, health status, and other factors. The research cited represents potential benefits and does not guarantee specific outcomes for all users.
Benefits
Benefits
- Helps reduce stress and emotional overwhelm*
- Supports hormonal balance during perimenopause and menopause*
- Promotes better sleep without melatonin or drowsiness*
- Non-habit forming and gentle on the stomach
Ingredients
Ingredients
Ashwagandha (Withania somnifera)(root), Black Pepper (Piper nigrum)(fruit), pullulan capsules.
Directions
Directions
Take one (1) capsule twice a day as a dietary supplement. For best results, take 20-30 min before a meal with an 8oz glass of water or as directed by your healthcare professional.
Warning
Warning
Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Warning: This product is not intended to diagnose, treat, cure or prevent any disease. Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.
Certificate of Analysis
Certificate of Analysis
-
Cardiovascular Health
-
Mental Focus
-
Improves Sleep
Benefits of Mood & Sleep Support
+ Builds stress resilience
+ Builds stress resilience
Daily Ashwagandha supplementation improves physiological, cognitive, and psychological stress response over 30 days.
+ Supports cardiovascular health
+ Supports cardiovascular health
At least two studies have found that Ashwagandha can raise VO2 max levels, the highest amount of oxygen you can take in when exercising.
+ Improves sleep
+ Improves sleep
A recent study confirms that Ashwagandha root extract can improve sleep quality and help manage insomnia by relaxing the body.
+ Increases mental focus
+ Increases mental focus
Ashwagandha aids in the enhancement of cognition, memory, and the capacity to perform motor reactions.
Daily Ashwagandha supplementation improves physiological, cognitive, and psychological stress response over 30 days.
At least two studies have found that Ashwagandha can raise VO2 max levels, the highest amount of oxygen you can take in when exercising.
A recent study confirms that Ashwagandha root extract can improve sleep quality and help manage insomnia by relaxing the body.
Ashwagandha aids in the enhancement of cognition, memory, and the capacity to perform motor reactions.
Success Stories of our Customers
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What's the shipping cost?
On average all order shipping costs are $4.5 to any state in the US. International shipping costs may vary.
When will I receive my products?
All products are shipped out from our fulfilment center within 4-6 business days and on average it takes 1-5 business days to deliver your order. If things go smoothly, you place your order on Monday you should receive it by Friday the same week.
Every now and then, such as holiday seasons, there may be a delay on orders due to the high volume coming in within such a short time period. We value being transparent with our customers, so please be patient as we are a small team doing the best we can! Thanks for your understanding.
What's your return policy?
In case you receive a product that has been damaged during shipment we will automatically ship out new product for you or issue a full refund. Refer to refund policy on footer of page. If you cancel a non subscription before the order is confirmed to ship you will be issued a full refund.
Where are the products manufactured?
This product is produced under strict quality control standards, ensuring you receive a premium product every time.
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Once you will make a purchase and your order will be confirmed, we will send out an order tracking link.
60 day hassle-free returns
We have a no-questions-asked returns policy. Just drop us a line within 60 days and consider it done.